Fem Support™ contains an exclusive standardized genistein, black cohosh, and dong quai extract which have been the subject of many scientific studies including those based around efficacy, safety, and restful sleep found in FemSupport’s™ formula. It has been proven effective and natural intervention for menopausal symptoms.
| Study Design | Benifits | Dosage | Reference |
| 1) Randomized, double-blind, controlled 3-month study which enrolled 244 menopausal patients, aged 40-60 years. The primary endpoint was the Kupperman Menopause Index (KMI0 and the frequency of adverse events at the end of treatment. |
– As effective as other HRT for menopausal symptoms. – Confirms the safety of specific Cimicifuga extracts, particularly FemSupport, for use in women with prei- and post menopausal climcteric symptoms. |
40 mg qd |
Bai W, Henneike-von Zepelin HH, Wang S, Zheng S, Liu J, Zhang Z, Geng L, Hu L, Jiao C, Liske E. Efficancy and tolerability of a medicinal product containing an isopropanolic black cohosh extract in Chinese women with menopausal symptoms: a randomized, double blind, parallel-controlled study versus tibolone. Maturitas. 2007 20;58:31-41. |
| 2) Twelve-week, randomized, multicenter, double- blind clinical trial comparing the efficacy and tolerability of FemSupport ® in the treatment of climacteric complaints compared with placebo. The primary efficacy measure was the change from baseline on the Menopause Rating Scale I. |
– FemSupport® effectively relieved menopausal symptoms, particularly in women in the early stages of menopause -Most significant reduction was in hot flash occurrence -Other symptoms resulting in significant reduction include: psyche (irritability and memory), and atrophy (vaginal dryness) |
40 mg qd |
Osmers R, et al. Efficacy and safety ofisopropanolic black cohosh extract for climacteric symptoms. Obstet Gynecol. 2005 May;105(5):1074-83. |
| 3) A review of 29 randomized controlled trials of complementary and alternative therapies for menopausal symptoms. |
Black cohosh is one of the only herbal remedies shown to be effective for menopausal symptoms, especially hot flashes |
40 mg qd |
Kronenberg F. Fugh-Berman A. Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials. Ann Intern Med. 2002 Nov 19;137 (10):805-13. |
| 4) Double-blind study involving the use of FemSupport® in women aged 43 to 60 with menopausal complaints lasting 6 months. |
Majority of women saw a 70% reduction in physical and emotional symptoms after 12 weeks, including hot flashes, night sweats, mood swings, and irritability. Significant improvement was noted after 4 weeks use Does not affect hormone levels or vaginal cytology (pap smear) |
40 mg qd |
Liske J, et al. Physiological investigation of a unique extract of black cohosh (Cimicifugae racemosae rhizoma): a 6-month clinical study demonstrates no systemic estrogenic effect. J Womens Health Gend Based Med. 2002 Mar;11(2):163-74. |
| 5) Women aged 46 to 58 with menopausal complaints were studied in a double-blind, 12-week, placebo-controlled trial. |
FemSupport® decreased the physical symptoms of menopause by approximately 60% (Kupperman Menopausal Index) Daily hot flashes decreased by 86% (from 4.9 to 0.7 per day) Emotional complaints were also dramatically reduced. |
4 mg dry extra bid (equal to 2 FemSupport tablets |
Stoll W. Phytopharmacon influences atrophic vaginal epithelium: Double blind study – cimicifuga vs. estrogenic substances. 1987. |
| 6) Four-week multi-center observational cohort study involving 518 individuals with difficulties falling asleep or staying asleep (Average age: 51 years, 73% women) |
At 2 weeks, 69% of participants experienced improvement in sleep qualitySupplementation reduced symptoms by an average of 88% after 4 weeks, including falling asleep, staying asleep and quality of sleep.
27% of participants were symptom-free after 4 weeks |
1 to 2 tablets, bid-tid. Each tablet contains: 75 mg V 23 mg H 45 mg LB |
Friede M, et al. Herbal agents for the treatment of insomnia. Neurol Psych. 1997;11:697-700. |
| 7) Eight-week, multi-center, non-interventional observational cohort trial with 830 individuals experiencing difficulties falling asleep or stayingasleep (Average age: 53 years, 72% women) |
After 4 weeks, symptoms of fatigue and occasional restlessness improved by more than 80% |
1 to 2 tablets, tid. Each tablet contains: 75 mg V, 23 mg H, 45 mg LB |
Volk S, et al. Phytosedative for the treatment of nervous restlessness and insomnia. Zeitschrift für Phytotherapie. 1999;20(6):337-344. |
| 8) Randomized, multi-center, double-blind and placebo controlled clinical trial. |
Demonstrated that there is little supportive evidence for a significant hepatotoxic risk due to black cohosh use. |
Naser B. Placebo-controlled trial shows no effects of an isopropanolic black cohosh extract on liver function. Presented at the American College of Obstetricians and Gynecologists Annual Clinical Meeting. Chicago, IL. 2009. |